Aamir Ahmed , Dr Graham Simpson , Adrian Bell and David Gollancz respond to a letter by a reader whose husband died of the disease after delaying getting a PSA test

It is understandable for patients suffering from a late diagnosis of prostate cancer, or families who have lost loved ones, to demand that something should be done ( Letters, 5 December ). I, however, respect the UK National Screening Committee’s recommendation not to screen most men using the prostate specific antigen (PSA) test.

The job of the committee was to weigh up the benefits and harms of any available test for routine screening. PSA testing, as a first step to diagnose cancer, results in false negatives and a significant number of false positives, meaning it has both low sensitivity and low specificity, making it a poor screening marker. PSA screening has been conducted in the US; there are varying estimates that, over three decades, it has resulted in more than 1 million patients receiving treatment (eg surgery or radiotherapy) they did not need.

Aamir Ahmed , Dr Graham Simpson , Adrian Bell and David Gollancz respond to a letter by a reader whose husband died of the disease after delaying getting a PSA test

It is understandable for patients suffering from a late diagnosis of prostate cancer, or families who have lost loved ones, to demand that something should be done ( Letters, 5 December ). I, however, respect the UK National Screening Committee’s recommendation not to screen most men using the prostate specific antigen (PSA) test.

The job of the committee was to weigh up the benefits and harms of any available test for routine screening. PSA testing, as a first step to diagnose cancer, results in false negatives and a significant number of false positives, meaning it has both low sensitivity and low specificity, making it a poor screening marker. PSA screening has been conducted in the US; there are varying estimates that, over three decades, it has resulted in more than 1 million patients receiving treatment (eg surgery or radiotherapy) they did not need.

Aamir Ahmed , Dr Graham Simpson , Adrian Bell and David Gollancz respond to a letter by a reader whose husband died of the disease after delaying getting a PSA test

It is understandable for patients suffering from a late diagnosis of prostate cancer, or families who have lost loved ones, to demand that something should be done ( Letters, 5 December ). I, however, respect the UK National Screening Committee’s recommendation not to screen most men using the prostate specific antigen (PSA) test.

The job of the committee was to weigh up the benefits and harms of any available test for routine screening. PSA testing, as a first step to diagnose cancer, results in false negatives and a significant number of false positives, meaning it has both low sensitivity and low specificity, making it a poor screening marker. PSA screening has been conducted in the US; there are varying estimates that, over three decades, it has resulted in more than 1 million patients receiving treatment (eg surgery or radiotherapy) they did not need.

Defying the will of the House of Commons will increase calls for radical reform of the upper house sooner rather than later, say the MPs Nia Griffith, Justin Madders and Debbie Abrahams

When visitors come to parliament, it seems incongruous to explain that, in our mother of parliaments, we have a second chamber – the House of Lords – which is unelected. Those who support its existence in its current or similar form justify it on the grounds that it performs a useful revising function which can improve the detail of legislation, and it undoubtedly does good work.

But the fact that it is unelected can only be tolerated in a democracy provided its members accept that it is for the House of Commons to have the last word on what becomes law and what doesn’t in this country.

Defying the will of the House of Commons will increase calls for radical reform of the upper house sooner rather than later, say the MPs Nia Griffith, Justin Madders and Debbie Abrahams

When visitors come to parliament, it seems incongruous to explain that, in our mother of parliaments, we have a second chamber – the House of Lords – which is unelected. Those who support its existence in its current or similar form justify it on the grounds that it performs a useful revising function which can improve the detail of legislation, and it undoubtedly does good work.

But the fact that it is unelected can only be tolerated in a democracy provided its members accept that it is for the House of Commons to have the last word on what becomes law and what doesn’t in this country.

Defying the will of the House of Commons will increase calls for radical reform of the upper house sooner rather than later, say the MPs Nia Griffith, Justin Madders and Debbie Abrahams

When visitors come to parliament, it seems incongruous to explain that, in our mother of parliaments, we have a second chamber – the House of Lords – which is unelected. Those who support its existence in its current or similar form justify it on the grounds that it performs a useful revising function which can improve the detail of legislation, and it undoubtedly does good work.

But the fact that it is unelected can only be tolerated in a democracy provided its members accept that it is for the House of Commons to have the last word on what becomes law and what doesn’t in this country.

In response to an article about a beaver spotted in Norfolk, Richard Foster reports sightings in Berkshire

In your article ( ‘No one knows where it came from’: first wild beaver spotted in Norfolk in 500 years, 7 December ), you quote the Beaver Trust as saying that, as well as Norfolk, wild beavers have been spotted in Kent, Hampshire, Somerset, Wiltshire and Herefordshire.

I can tell you that we also have beavers in Berkshire. I live by the River Kennet and I caught one on my garden trail camera in August, along with otters in the same 30-second clip. The identification of the beaver is unmistakable, and was confirmed by the Berks, Bucks and Oxon wildlife trust. Two weeks ago, my neighbour caught a beaver on her garden trail camera. Her garden is 50 yards downstream of ours.

In response to an article about a beaver spotted in Norfolk, Richard Foster reports sightings in Berkshire

In your article ( ‘No one knows where it came from’: first wild beaver spotted in Norfolk in 500 years, 7 December ), you quote the Beaver Trust as saying that, as well as Norfolk, wild beavers have been spotted in Kent, Hampshire, Somerset, Wiltshire and Herefordshire.

I can tell you that we also have beavers in Berkshire. I live by the River Kennet and I caught one on my garden trail camera in August, along with otters in the same 30-second clip. The identification of the beaver is unmistakable, and was confirmed by the Berks, Bucks and Oxon wildlife trust. Two weeks ago, my neighbour caught a beaver on her garden trail camera. Her garden is 50 yards downstream of ours.

In response to an article about a beaver spotted in Norfolk, Richard Foster reports sightings in Berkshire

In your article ( ‘No one knows where it came from’: first wild beaver spotted in Norfolk in 500 years, 7 December ), you quote the Beaver Trust as saying that, as well as Norfolk, wild beavers have been spotted in Kent, Hampshire, Somerset, Wiltshire and Herefordshire.

I can tell you that we also have beavers in Berkshire. I live by the River Kennet and I caught one on my garden trail camera in August, along with otters in the same 30-second clip. The identification of the beaver is unmistakable, and was confirmed by the Berks, Bucks and Oxon wildlife trust. Two weeks ago, my neighbour caught a beaver on her garden trail camera. Her garden is 50 yards downstream of ours.