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    The Guardian

    people 438 subscribers • The need for independent journalism has never been greater.

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      Could a drug for narcolepsy change the world? | Zoe Williams

      news.movim.eu / TheGuardian • 9 December 2025 • 1 minute

    There are apparently breakthroughs on the way for those with sleep disorders – which sent me down a rabbit hole of research...

    I met a guy in pharmaceuticals who told me about a bunch of cool breakthroughs in sleep meds: mainly, we may be on the brink of a new Wegovy, but in this case it’s a drug to cure narcolepsy. I suggested the two things are not quite the same, given that obesity is a global epidemic and narcolepsy is fairly rare. He countered that the way the drug works might also have applications for insomnia; similar to the Post-it note having been invented by someone trying to create the world’s strongest glue .

    Anyway, in the course of this, I discovered the test for type 1 narcolepsy, which is that you’re put in a room with zero stimulation – nothing to read, no one to chat to, perfect silence, perfect temperature – and timed on how long it takes you to fall asleep. If it’s under eight minutes, you’re narcoleptic. But the average, for a person with no complaints in that area at all, is 22 minutes. I was completely incredulous. This is a grip on consciousness more or less the same as a house cat. Bored? Go to sleep. Even a dog will have a quick look for something to eat first.

    Continue reading...
    • tagsleep tagsleep tagsleep taghealth & wellbeing taghealth & wellbeing taghealth & wellbeing tagscience tagscience tagscience taglife and style taglife and style taglife and style tagsleep tagsleep tagsleep taghealth & wellbeing taghealth & wellbeing taghealth & wellbeing tagscience tagscience tagscience taglife and style taglife and style taglife and style tagsleep tagsleep tagsleep taghealth & wellbeing taghealth & wellbeing taghealth & wellbeing tagscience tagscience tagscience taglife and style taglife and style taglife and style

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      Could a drug for narcolepsy change the world? | Zoe Williams

      news.movim.eu / TheGuardian • 9 December 2025 • 1 minute

    There are apparently breakthroughs on the way for those with sleep disorders – which sent me down a rabbit hole of research...

    I met a guy in pharmaceuticals who told me about a bunch of cool breakthroughs in sleep meds: mainly, we may be on the brink of a new Wegovy, but in this case it’s a drug to cure narcolepsy. I suggested the two things are not quite the same, given that obesity is a global epidemic and narcolepsy is fairly rare. He countered that the way the drug works might also have applications for insomnia; similar to the Post-it note having been invented by someone trying to create the world’s strongest glue .

    Anyway, in the course of this, I discovered the test for type 1 narcolepsy, which is that you’re put in a room with zero stimulation – nothing to read, no one to chat to, perfect silence, perfect temperature – and timed on how long it takes you to fall asleep. If it’s under eight minutes, you’re narcoleptic. But the average, for a person with no complaints in that area at all, is 22 minutes. I was completely incredulous. This is a grip on consciousness more or less the same as a house cat. Bored? Go to sleep. Even a dog will have a quick look for something to eat first.

    Continue reading...
    • tagsleep tagsleep tagsleep taghealth & wellbeing taghealth & wellbeing taghealth & wellbeing tagscience tagscience tagscience taglife and style taglife and style taglife and style tagsleep tagsleep tagsleep taghealth & wellbeing taghealth & wellbeing taghealth & wellbeing tagscience tagscience tagscience taglife and style taglife and style taglife and style tagsleep tagsleep tagsleep taghealth & wellbeing taghealth & wellbeing taghealth & wellbeing tagscience tagscience tagscience taglife and style taglife and style taglife and style

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      Could a drug for narcolepsy change the world? | Zoe Williams

      news.movim.eu / TheGuardian • 9 December 2025 • 1 minute

    There are apparently breakthroughs on the way for those with sleep disorders – which sent me down a rabbit hole of research...

    I met a guy in pharmaceuticals who told me about a bunch of cool breakthroughs in sleep meds: mainly, we may be on the brink of a new Wegovy, but in this case it’s a drug to cure narcolepsy. I suggested the two things are not quite the same, given that obesity is a global epidemic and narcolepsy is fairly rare. He countered that the way the drug works might also have applications for insomnia; similar to the Post-it note having been invented by someone trying to create the world’s strongest glue .

    Anyway, in the course of this, I discovered the test for type 1 narcolepsy, which is that you’re put in a room with zero stimulation – nothing to read, no one to chat to, perfect silence, perfect temperature – and timed on how long it takes you to fall asleep. If it’s under eight minutes, you’re narcoleptic. But the average, for a person with no complaints in that area at all, is 22 minutes. I was completely incredulous. This is a grip on consciousness more or less the same as a house cat. Bored? Go to sleep. Even a dog will have a quick look for something to eat first.

    Continue reading...
    • tagsleep tagsleep tagsleep taghealth & wellbeing taghealth & wellbeing taghealth & wellbeing tagscience tagscience tagscience taglife and style taglife and style taglife and style tagsleep tagsleep tagsleep taghealth & wellbeing taghealth & wellbeing taghealth & wellbeing tagscience tagscience tagscience taglife and style taglife and style taglife and style tagsleep tagsleep tagsleep taghealth & wellbeing taghealth & wellbeing taghealth & wellbeing tagscience tagscience tagscience taglife and style taglife and style taglife and style

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      David Squires on … Mohamed Salah’s explosive interview and Liverpool chaos

      news.movim.eu / TheGuardian • 9 December 2025

    Our cartoonist on the trouble at Anfield after Egyptian’s stinging response to being dropped by Arne Slot

    • David’s favourite cartoons of 2025 | Buy one here

    • And his latest book, Chaos in the Box: get it now

    Continue reading...
    • tagfootball tagfootball tagfootball tagsport tagsport tagsport tagmohamed salah tagmohamed salah tagmohamed salah tagliverpool tagliverpool tagliverpool tagfootball tagfootball tagfootball tagsport tagsport tagsport tagmohamed salah tagmohamed salah tagmohamed salah tagliverpool tagliverpool tagliverpool tagfootball tagfootball tagfootball tagsport tagsport tagsport tagmohamed salah tagmohamed salah tagmohamed salah tagliverpool tagliverpool tagliverpool

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      David Squires on … Mohamed Salah’s explosive interview and Liverpool chaos

      news.movim.eu / TheGuardian • 9 December 2025

    Our cartoonist on the trouble at Anfield after Egyptian’s stinging response to being dropped by Arne Slot

    • David’s favourite cartoons of 2025 | Buy one here

    • And his latest book, Chaos in the Box: get it now

    Continue reading...
    • tagfootball tagfootball tagfootball tagsport tagsport tagsport tagmohamed salah tagmohamed salah tagmohamed salah tagliverpool tagliverpool tagliverpool tagfootball tagfootball tagfootball tagsport tagsport tagsport tagmohamed salah tagmohamed salah tagmohamed salah tagliverpool tagliverpool tagliverpool tagfootball tagfootball tagfootball tagsport tagsport tagsport tagmohamed salah tagmohamed salah tagmohamed salah tagliverpool tagliverpool tagliverpool

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      David Squires on … Mohamed Salah’s explosive interview and Liverpool chaos

      news.movim.eu / TheGuardian • 9 December 2025

    Our cartoonist on the trouble at Anfield after Egyptian’s stinging response to being dropped by Arne Slot

    • David’s favourite cartoons of 2025 | Buy one here

    • And his latest book, Chaos in the Box: get it now

    Continue reading...
    • tagfootball tagfootball tagfootball tagsport tagsport tagsport tagmohamed salah tagmohamed salah tagmohamed salah tagliverpool tagliverpool tagliverpool tagfootball tagfootball tagfootball tagsport tagsport tagsport tagmohamed salah tagmohamed salah tagmohamed salah tagliverpool tagliverpool tagliverpool tagfootball tagfootball tagfootball tagsport tagsport tagsport tagmohamed salah tagmohamed salah tagmohamed salah tagliverpool tagliverpool tagliverpool

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      Hannigan/Chamayou review – strange and beautiful musical magic

      news.movim.eu / TheGuardian • 9 December 2025

    Wigmore Hall, London
    Barbara Hannigan and Bertrand Chamayou were exhilarating and extraordinary in John Zorn’s monumental Jumalattaret; a beautifully intimate performance of Messiaen’s Chants de Terre et de Ciel completed an enthralling evening

    One generation’s “unperformable” is another’s repertoire staple. Tristan und Isolde, Tchaikovsky’s First Piano Concerto and Beethoven’s Ninth were all once declared beyond reach. But when Barbara Hannigan – the fearless, seemingly limitless soprano with more than 100 world premieres to her name – admits that a work came close, reducing her to “a state of panic” over a multi-year study period, you believe her.

    Inspired by Finland’s national epic the Kalevala, John Zorn’s Jumalattaret is less a song-cycle than a musical seance, summoning a series of spirits and goddesses in sound. The singer morphs from persona to persona in yelps and keening cries, guttural moans and shouts, sometimes anchored, sometimes released by the piano (here Bertrand Chamayou) – an ever-present sorcerer’s assistant.

    Continue reading...
    • tagclassical music tagclassical music tagclassical music tagculture tagculture tagculture tagmusic tagmusic tagmusic tagclassical music tagclassical music tagclassical music tagculture tagculture tagculture tagmusic tagmusic tagmusic tagclassical music tagclassical music tagclassical music tagculture tagculture tagculture tagmusic tagmusic tagmusic

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      Hannigan/Chamayou review – strange and beautiful musical magic

      news.movim.eu / TheGuardian • 9 December 2025

    Wigmore Hall, London
    Barbara Hannigan and Bertrand Chamayou were exhilarating and extraordinary in John Zorn’s monumental Jumalattaret; a beautifully intimate performance of Messiaen’s Chants de Terre et de Ciel completed an enthralling evening

    One generation’s “unperformable” is another’s repertoire staple. Tristan und Isolde, Tchaikovsky’s First Piano Concerto and Beethoven’s Ninth were all once declared beyond reach. But when Barbara Hannigan – the fearless, seemingly limitless soprano with more than 100 world premieres to her name – admits that a work came close, reducing her to “a state of panic” over a multi-year study period, you believe her.

    Inspired by Finland’s national epic the Kalevala, John Zorn’s Jumalattaret is less a song-cycle than a musical seance, summoning a series of spirits and goddesses in sound. The singer morphs from persona to persona in yelps and keening cries, guttural moans and shouts, sometimes anchored, sometimes released by the piano (here Bertrand Chamayou) – an ever-present sorcerer’s assistant.

    Continue reading...
    • tagclassical music tagclassical music tagclassical music tagculture tagculture tagculture tagmusic tagmusic tagmusic tagclassical music tagclassical music tagclassical music tagculture tagculture tagculture tagmusic tagmusic tagmusic tagclassical music tagclassical music tagclassical music tagculture tagculture tagculture tagmusic tagmusic tagmusic

    • Pictures 3 image

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    • chevron_right

      Hannigan/Chamayou review – strange and beautiful musical magic

      news.movim.eu / TheGuardian • 9 December 2025

    Wigmore Hall, London
    Barbara Hannigan and Bertrand Chamayou were exhilarating and extraordinary in John Zorn’s monumental Jumalattaret; a beautifully intimate performance of Messiaen’s Chants de Terre et de Ciel completed an enthralling evening

    One generation’s “unperformable” is another’s repertoire staple. Tristan und Isolde, Tchaikovsky’s First Piano Concerto and Beethoven’s Ninth were all once declared beyond reach. But when Barbara Hannigan – the fearless, seemingly limitless soprano with more than 100 world premieres to her name – admits that a work came close, reducing her to “a state of panic” over a multi-year study period, you believe her.

    Inspired by Finland’s national epic the Kalevala, John Zorn’s Jumalattaret is less a song-cycle than a musical seance, summoning a series of spirits and goddesses in sound. The singer morphs from persona to persona in yelps and keening cries, guttural moans and shouts, sometimes anchored, sometimes released by the piano (here Bertrand Chamayou) – an ever-present sorcerer’s assistant.

    Continue reading...
    • tagclassical music tagclassical music tagclassical music tagculture tagculture tagculture tagmusic tagmusic tagmusic tagclassical music tagclassical music tagclassical music tagculture tagculture tagculture tagmusic tagmusic tagmusic tagclassical music tagclassical music tagclassical music tagculture tagculture tagculture tagmusic tagmusic tagmusic

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