Blockbuster weight-loss and diabetes drugs Wegovy and Ozempic top the list of 15 drugs selected for the second round of federal price negotiations, which are scheduled to begin this year, with resulting bargained prices going into effect in 2027.

The first round of negotiations , involving 10 high-cost drugs, wrapped up in August, with resulting prices being 38 percent to 79 percent lower than list prices. Those negotiated prices will go into effect in 2026 and are expected to save people with Medicare prescription drug coverage $1.5 billion in out-of-pocket costs.

“Last year we proved that negotiating for lower drug prices works," Xavier Becerra, secretary of the Department of Health and Human Services (HHS), said in a statement. "Now we plan to build on that record by negotiating for lower prices for 15 additional important drugs for seniors."

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Blockbuster weight-loss and diabetes drugs Wegovy and Ozempic top the list of 15 drugs selected for the second round of federal price negotiations, which are scheduled to begin this year, with resulting bargained prices going into effect in 2027.

The first round of negotiations , involving 10 high-cost drugs, wrapped up in August, with resulting prices being 38 percent to 79 percent lower than list prices. Those negotiated prices will go into effect in 2026 and are expected to save people with Medicare prescription drug coverage $1.5 billion in out-of-pocket costs.

“Last year we proved that negotiating for lower drug prices works," Xavier Becerra, secretary of the Department of Health and Human Services (HHS), said in a statement. "Now we plan to build on that record by negotiating for lower prices for 15 additional important drugs for seniors."

Read full article

Comments

Blockbuster weight-loss and diabetes drugs Wegovy and Ozempic top the list of 15 drugs selected for the second round of federal price negotiations, which are scheduled to begin this year, with resulting bargained prices going into effect in 2027.

The first round of negotiations , involving 10 high-cost drugs, wrapped up in August, with resulting prices being 38 percent to 79 percent lower than list prices. Those negotiated prices will go into effect in 2026 and are expected to save people with Medicare prescription drug coverage $1.5 billion in out-of-pocket costs.

“Last year we proved that negotiating for lower drug prices works," Xavier Becerra, secretary of the Department of Health and Human Services (HHS), said in a statement. "Now we plan to build on that record by negotiating for lower prices for 15 additional important drugs for seniors."

Read full article

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Apple released new beta versions of iOS 18.3 to developers and the public yesterday, and one of the changes coming with the new software update will (at least temporarily) disable Apple Intelligence notification summaries for all apps in the App Store's News and Entertainment category, at least temporarily.

Apple said earlier this month that it would be instituting updates to how these notifications are handled after complaints from news organizations, and the company has apparently decided to turn them off entirely while it decides what those updates will look like. Most prominently, one user's notification summary from the BBC suggested that Luigi Mangione, the alleged killer of UnitedHealthcare CEO Brian Thompson, had died of suicide; this was not true. Other examples have been cropping up since then.

For the notification summaries that remain, Apple is instituting changes to make it clearer when users are reading summaries and to make it easier to turn those summaries off. Notification summaries in iOS 18.3 will be italicized to help further distinguish them from individual non-summarized notifications—before, there was a small icon next to the text to indicate you were looking at a summary. Apple is also making it possible to turn off summaries on a per-app basis directly from the lock screen without diving into the Settings app to do it.

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Apple released new beta versions of iOS 18.3 to developers and the public yesterday, and one of the changes coming with the new software update will (at least temporarily) disable Apple Intelligence notification summaries for all apps in the App Store's News and Entertainment category, at least temporarily.

Apple said earlier this month that it would be instituting updates to how these notifications are handled after complaints from news organizations, and the company has apparently decided to turn them off entirely while it decides what those updates will look like. Most prominently, one user's notification summary from the BBC suggested that Luigi Mangione, the alleged killer of UnitedHealthcare CEO Brian Thompson, had died of suicide; this was not true. Other examples have been cropping up since then.

For the notification summaries that remain, Apple is instituting changes to make it clearer when users are reading summaries and to make it easier to turn those summaries off. Notification summaries in iOS 18.3 will be italicized to help further distinguish them from individual non-summarized notifications—before, there was a small icon next to the text to indicate you were looking at a summary. Apple is also making it possible to turn off summaries on a per-app basis directly from the lock screen without diving into the Settings app to do it.

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Apple released new beta versions of iOS 18.3 to developers and the public yesterday, and one of the changes coming with the new software update will (at least temporarily) disable Apple Intelligence notification summaries for all apps in the App Store's News and Entertainment category, at least temporarily.

Apple said earlier this month that it would be instituting updates to how these notifications are handled after complaints from news organizations, and the company has apparently decided to turn them off entirely while it decides what those updates will look like. Most prominently, one user's notification summary from the BBC suggested that Luigi Mangione, the alleged killer of UnitedHealthcare CEO Brian Thompson, had died of suicide; this was not true. Other examples have been cropping up since then.

For the notification summaries that remain, Apple is instituting changes to make it clearer when users are reading summaries and to make it easier to turn those summaries off. Notification summaries in iOS 18.3 will be italicized to help further distinguish them from individual non-summarized notifications—before, there was a small icon next to the text to indicate you were looking at a summary. Apple is also making it possible to turn off summaries on a per-app basis directly from the lock screen without diving into the Settings app to do it.

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Lithium may be the key component in most modern batteries, but it doesn't make up the bulk of the material used in them. Instead, much of the material is in the electrodes, where the lithium gets stored when the battery isn't charging or discharging. So one way to make lighter and more compact lithium-ion batteries is to find electrode materials that can store more lithium. That's one of the reasons that recent generations of batteries are starting to incorporate silicon into the electrode materials.

There are materials that can store even more lithium than silicon; a notable example is sulfur. But sulfur has a tendency to react with itself, producing ions that can float off into the electrolyte. Plus, like any electrode material, it tends to expand in proportion to the amount of lithium that gets stored, which can create physical strains on the battery's structure. So while it has been easy to make lithium-sulfur batteries, their performance has tended to degrade rapidly.

But this week, researchers described a lithium-sulfur battery that still has over 80 percent of its original capacity after 25,000 charge/discharge cycles. All it took was a solid electrolyte that was more reactive than the sulfur itself.

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Lithium may be the key component in most modern batteries, but it doesn't make up the bulk of the material used in them. Instead, much of the material is in the electrodes, where the lithium gets stored when the battery isn't charging or discharging. So one way to make lighter and more compact lithium-ion batteries is to find electrode materials that can store more lithium. That's one of the reasons that recent generations of batteries are starting to incorporate silicon into the electrode materials.

There are materials that can store even more lithium than silicon; a notable example is sulfur. But sulfur has a tendency to react with itself, producing ions that can float off into the electrolyte. Plus, like any electrode material, it tends to expand in proportion to the amount of lithium that gets stored, which can create physical strains on the battery's structure. So while it has been easy to make lithium-sulfur batteries, their performance has tended to degrade rapidly.

But this week, researchers described a lithium-sulfur battery that still has over 80 percent of its original capacity after 25,000 charge/discharge cycles. All it took was a solid electrolyte that was more reactive than the sulfur itself.

Read full article

Comments

Lithium may be the key component in most modern batteries, but it doesn't make up the bulk of the material used in them. Instead, much of the material is in the electrodes, where the lithium gets stored when the battery isn't charging or discharging. So one way to make lighter and more compact lithium-ion batteries is to find electrode materials that can store more lithium. That's one of the reasons that recent generations of batteries are starting to incorporate silicon into the electrode materials.

There are materials that can store even more lithium than silicon; a notable example is sulfur. But sulfur has a tendency to react with itself, producing ions that can float off into the electrolyte. Plus, like any electrode material, it tends to expand in proportion to the amount of lithium that gets stored, which can create physical strains on the battery's structure. So while it has been easy to make lithium-sulfur batteries, their performance has tended to degrade rapidly.

But this week, researchers described a lithium-sulfur battery that still has over 80 percent of its original capacity after 25,000 charge/discharge cycles. All it took was a solid electrolyte that was more reactive than the sulfur itself.

Read full article

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