For those of us whose memory of high school biology hasn't faded entirely, planarians will probably sound very familiar. They're generally used as an example of one of the extreme ends of regenerative capacity. While some animals like mammals have a limited ability to regenerate lost tissues, planarians can be cut roughly in half and regenerate either an entire head or entire tail, depending on which part of the body you choose to keep track of.

In doing so, they have to re-establish something that is typically only needed early in an animal's development: a signaling system that helps tell cells where the animal's head and tail are. Now, a US-based team asked a question that I'd never have thought of: What happens if you cut the animal in half early in development, while the developmental head-to-tail signaling system is still active? The answer turned out to be surprisingly complex.

Heads or tails?

Planarians are small flatworms that would probably be living quiet lives somewhere if biologists hadn't discovered their ability to regenerate lots of adult tissues when damaged. The process has been well-studied by this point and involves the formation of a cluster of stem cells, called a blastema, at the site of damage. From there, many of the signals that control the formation of specialized tissues in the embryo get re-activated, directing the stem cells down the developmental pathways needed to reproduce any lost organs.

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For those of us whose memory of high school biology hasn't faded entirely, planarians will probably sound very familiar. They're generally used as an example of one of the extreme ends of regenerative capacity. While some animals like mammals have a limited ability to regenerate lost tissues, planarians can be cut roughly in half and regenerate either an entire head or entire tail, depending on which part of the body you choose to keep track of.

In doing so, they have to re-establish something that is typically only needed early in an animal's development: a signaling system that helps tell cells where the animal's head and tail are. Now, a US-based team asked a question that I'd never have thought of: What happens if you cut the animal in half early in development, while the developmental head-to-tail signaling system is still active? The answer turned out to be surprisingly complex.

Heads or tails?

Planarians are small flatworms that would probably be living quiet lives somewhere if biologists hadn't discovered their ability to regenerate lots of adult tissues when damaged. The process has been well-studied by this point and involves the formation of a cluster of stem cells, called a blastema, at the site of damage. From there, many of the signals that control the formation of specialized tissues in the embryo get re-activated, directing the stem cells down the developmental pathways needed to reproduce any lost organs.

Read full article

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For those of us whose memory of high school biology hasn't faded entirely, planarians will probably sound very familiar. They're generally used as an example of one of the extreme ends of regenerative capacity. While some animals like mammals have a limited ability to regenerate lost tissues, planarians can be cut roughly in half and regenerate either an entire head or entire tail, depending on which part of the body you choose to keep track of.

In doing so, they have to re-establish something that is typically only needed early in an animal's development: a signaling system that helps tell cells where the animal's head and tail are. Now, a US-based team asked a question that I'd never have thought of: What happens if you cut the animal in half early in development, while the developmental head-to-tail signaling system is still active? The answer turned out to be surprisingly complex.

Heads or tails?

Planarians are small flatworms that would probably be living quiet lives somewhere if biologists hadn't discovered their ability to regenerate lots of adult tissues when damaged. The process has been well-studied by this point and involves the formation of a cluster of stem cells, called a blastema, at the site of damage. From there, many of the signals that control the formation of specialized tissues in the embryo get re-activated, directing the stem cells down the developmental pathways needed to reproduce any lost organs.

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In a Black Mirror -esque turn, some cash-strapped actors who didn't fully understand the consequences are regretting selling their likenesses to be used in AI videos that they consider embarrassing, damaging, or harmful, AFP reported .

Among them is a 29-year-old New York-based actor, Adam Coy, who licensed rights to his face and voice to a company called MCM for one year for $1,000 without thinking, "am I crossing a line by doing this?" His partner's mother later found videos where he appeared as a doomsayer predicting disasters, he told the AFP.

South Korean actor Simon Lee's AI likeness was similarly used to spook naïve Internet users but in a potentially more harmful way. He told the AFP that he was "stunned" to find his AI avatar promoting "questionable health cures on TikTok and Instagram," feeling ashamed to have his face linked to obvious scams.

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In a Black Mirror -esque turn, some cash-strapped actors who didn't fully understand the consequences are regretting selling their likenesses to be used in AI videos that they consider embarrassing, damaging, or harmful, AFP reported .

Among them is a 29-year-old New York-based actor, Adam Coy, who licensed rights to his face and voice to a company called MCM for one year for $1,000 without thinking, "am I crossing a line by doing this?" His partner's mother later found videos where he appeared as a doomsayer predicting disasters, he told the AFP.

South Korean actor Simon Lee's AI likeness was similarly used to spook naïve Internet users but in a potentially more harmful way. He told the AFP that he was "stunned" to find his AI avatar promoting "questionable health cures on TikTok and Instagram," feeling ashamed to have his face linked to obvious scams.

Read full article

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In a Black Mirror -esque turn, some cash-strapped actors who didn't fully understand the consequences are regretting selling their likenesses to be used in AI videos that they consider embarrassing, damaging, or harmful, AFP reported .

Among them is a 29-year-old New York-based actor, Adam Coy, who licensed rights to his face and voice to a company called MCM for one year for $1,000 without thinking, "am I crossing a line by doing this?" His partner's mother later found videos where he appeared as a doomsayer predicting disasters, he told the AFP.

South Korean actor Simon Lee's AI likeness was similarly used to spook naïve Internet users but in a potentially more harmful way. He told the AFP that he was "stunned" to find his AI avatar promoting "questionable health cures on TikTok and Instagram," feeling ashamed to have his face linked to obvious scams.

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After obliterating the federal office on long COVID and clawing back billions in COVID funding from state health departments, the Trump administration has now entirely erased the online hub for federal COVID-19 resources. In its place now stands a site promoting the unproven idea that the pandemic virus SARS-CoV-2 was generated in and leaked from a lab in China, sparking the global health crisis.

Navigating to COVID.gov brings up a slick site with rich content that lays out arguments and allegations supporting a lab-based origin of the pandemic and subsequent cover-up by US health officials and Democrats.

Previously, the site provided unembellished quick references to COVID-19 resources, including links to information on vaccines, testing, treatments, and long COVID. It also provided a link to resources for addressing COVID-19 vaccine misconceptions and confronting misinformation . That all appears to be gone now, though some of the same information still remains on a separate COVID-19 page hosted by the Centers for Disease Control and Prevention .

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After obliterating the federal office on long COVID and clawing back billions in COVID funding from state health departments, the Trump administration has now entirely erased the online hub for federal COVID-19 resources. In its place now stands a site promoting the unproven idea that the pandemic virus SARS-CoV-2 was generated in and leaked from a lab in China, sparking the global health crisis.

Navigating to COVID.gov brings up a slick site with rich content that lays out arguments and allegations supporting a lab-based origin of the pandemic and subsequent cover-up by US health officials and Democrats.

Previously, the site provided unembellished quick references to COVID-19 resources, including links to information on vaccines, testing, treatments, and long COVID. It also provided a link to resources for addressing COVID-19 vaccine misconceptions and confronting misinformation . That all appears to be gone now, though some of the same information still remains on a separate COVID-19 page hosted by the Centers for Disease Control and Prevention .

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After obliterating the federal office on long COVID and clawing back billions in COVID funding from state health departments, the Trump administration has now entirely erased the online hub for federal COVID-19 resources. In its place now stands a site promoting the unproven idea that the pandemic virus SARS-CoV-2 was generated in and leaked from a lab in China, sparking the global health crisis.

Navigating to COVID.gov brings up a slick site with rich content that lays out arguments and allegations supporting a lab-based origin of the pandemic and subsequent cover-up by US health officials and Democrats.

Previously, the site provided unembellished quick references to COVID-19 resources, including links to information on vaccines, testing, treatments, and long COVID. It also provided a link to resources for addressing COVID-19 vaccine misconceptions and confronting misinformation . That all appears to be gone now, though some of the same information still remains on a separate COVID-19 page hosted by the Centers for Disease Control and Prevention .

Read full article

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